EUDRAGIT® E PO

EUDRAGIT^® E PO is a cationic copolymer based on dimethylaminoethyl methacrylate, butyl methacrylate, and methyl methacrylate. 

Physical properties: It is a white powder with a characteristic amine-like odour.

Chemical structure:

Product Form: Powder
Targeted Drug Release Area: Stomach
Dissolution:

• Soluble in gastric fluid up to pH 5.0
• Swellable and permeable above pH 5.0

Characteristics:

• Low viscosity, high pigment binding capacity, good adhesion
• low polymer weight gain

CAS number: 24938 – 16 – 7
Chemical/IUPAC name: Poly(butyl methacylate-co-(2-dimethylaminoethyl) methacrylate-co-methyl methacrylate) 1:2:1
INCI name: Acrylates / Dimethylaminoethyl Methacrylate Copolymer 


Monographs:

       Ph. Eur.: Basic Butylated Methacrylate Copolymer
       USP/NF: polymer conforms to Amino Methacrylate Copolymer - NF 
      JPE: Aminoalkyl Methacrylate Copolymer E

GMP standard: The Joint IPEC – PQG Good Manufacturing Practice
Guide for Bulk Pharmaceutical Excipients 2006 and
USP-NF General Chapter <1078>

Drug Master file: #1242
Weight average molar mass: approx. 47,000 g/mol 
Alkali Value: 180 mg KOH/ g polymer
Glass Transition Temperature (Tg): ~48°C

An according EIP format is available on request.