EUDRAGIT® S 100

EUDRAGIT^® S 100 are anionic copolymers based on methacrylic acic and methyl methacrylate.

Physical properties: It is a solid substance in form of a white powder with a faint characteristic odour.

Chemical structure:

Form of Product: Powder
Targeted Drug Release Area: Colon delivery
Dissolution: pH 7.0

Characteristics:

• Granulation of drug substances in powder form for controlled release
• Effective and stable enteric coatings with a fast dissolution in the upper Bowel
• Site specific drug delivery in intestine by combination with EUDRAGIT^® S grades
• Variable release profiles

CAS number: 25086 – 15 – 1
Chemical/IUPAC name: Poly(methacylic acid-co-methyl methacrylate) 1:2
INCI name: Acrylates Copolymer

Monographs:

        Ph. Eur.: Methacrylic Acid - Methyl Methacrylate Copolymer (1:2)
        USP/NF: Methacrylic Acid Copolymer, Type B - NF
        JPE: Methacrylic Acid Copolymer S 
 

GMP standard: The Joint IPEC – PQG Good Manufacturing Practice
Guide for Bulk Pharmaceutical Excipients 2006 and
USP-NF General Chapter <1078>

Drug Master File: # 1242
Molecular weight information: approx. 125,000 g/mol
Acid Value: 190 mg KOH/ g polymer

An according EIP format is available on request